NONSTEROIDAL ANTIINFLAMMATORY AGENTS
\nˌɒnstˈɛɹɔ͡ɪdə͡l ˌantɪɪnflˈamətəɹˌi ˈe͡ɪd͡ʒənts], \nˌɒnstˈɛɹɔɪdəl ˌantɪɪnflˈamətəɹˌi ˈeɪdʒənts], \n_ˌɒ_n_s_t_ˈɛ_ɹ_ɔɪ_d_əl ˌa_n_t_ɪ__ɪ_n_f_l_ˈa_m_ə_t_ə_ɹ_ˌi_ ˈeɪ_dʒ_ə_n_t_s]\
Sort: Oldest first
-
Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or phospholipase C or may modulate T-cell function. (AMA Drug Evaluations Annual, 1994, p 1814-5)
By DataStellar Co., Ltd
Word of the day
dust storm
- a windstorm that lifts up clouds of dust or sand a windstorm that lifts up clouds dust or sand; "it was the kind of duster not experienced in years"
Nearby Words
- nonsteroid
- nonsteroidal
- nonsteroidal abortifacient agents
- nonsteroidal anti-inflammatory
- nonsteroidal anti-inflammatory drug
- Nonsteroidal Antiinflammatory Agents
- nonsteroidal estrogens
- nonstick
- nonstop
- nonstop flight
- nonstriated