MUDDLEHEAD

\mˈʌdə͡lhˌɛd], \mˈʌdə‍lhˌɛd], \m_ˈʌ_d_əl_h_ˌɛ_d]\

Definitions of MUDDLEHEAD

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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