MAC (CHROMOSOME)
\ˌɛmˌe͡ɪsˈiː kɹˈə͡ʊməsˌə͡ʊm], \ˌɛmˌeɪsˈiː kɹˈəʊməsˌəʊm], \ˌɛ_m_ˌeɪ_s_ˈiː__ k_ɹ_ˈəʊ_m_ə_s_ˌəʊ_m]\
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DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, that are required for successful replication, propagation to and maintainance in progeny mammalian cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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