LIGAMENTOUS PLATE
\lˌɪɡəmˈɛntəs plˈe͡ɪt], \lˌɪɡəmˈɛntəs plˈeɪt], \l_ˌɪ_ɡ_ə_m_ˈɛ_n_t_ə_s p_l_ˈeɪ_t]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.