LEAD-PIPE CONTRACTION

\lˈiːdpˈa͡ɪp kəntɹˈakʃən], \lˈiːdpˈa‍ɪp kəntɹˈakʃən], \l_ˈiː_d_p_ˈaɪ_p k_ə_n_t_ɹ_ˈa_k_ʃ_ə_n]\

Definitions of LEAD-PIPE CONTRACTION

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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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