KAP95 PROTEIN
\kˈap nˈa͡ɪntifˈa͡ɪv pɹˈə͡ʊtiːn], \kˈap nˈaɪntifˈaɪv pɹˈəʊtiːn], \k_ˈa_p n_ˈaɪ_n_t_i_f_ˈaɪ_v p_ɹ_ˈəʊ_t_iː_n]\
Sort: Oldest first
-
Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.