JUVENILE ABSENCE EPILEPSIES
\d͡ʒˈuːvənˌa͡ɪl ˈabsəns ˈɛpɪlˌɛpsɪz], \dʒˈuːvənˌaɪl ˈabsəns ˈɛpɪlˌɛpsɪz], \dʒ_ˈuː_v_ə_n_ˌaɪ_l ˈa_b_s_ə_n_s ˈɛ_p_ɪ_l_ˌɛ_p_s_ɪ_z]\
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A childhood seizure disorder characterized by rhythmic electrical brain discharges of geneneralized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the seizure. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
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Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.