JOHANNEAN
\d͡ʒˈə͡ʊhɐnˌi͡ən], \dʒˈəʊhɐnˌiən], \dʒ_ˈəʊ_h_ɐ_n_ˌiə_n]\
Definitions of JOHANNEAN
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.