INTERCALATING LIGANDS
\ˌɪntəkˈale͡ɪtɪŋ lˈɪɡandz], \ˌɪntəkˈaleɪtɪŋ lˈɪɡandz], \ˌɪ_n_t_ə_k_ˈa_l_eɪ_t_ɪ_ŋ l_ˈɪ_ɡ_a_n_d_z]\
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.