INSINUATOR
\ɪnsˈɪnjuːˌe͡ɪtə], \ɪnsˈɪnjuːˌeɪtə], \ɪ_n_s_ˈɪ_n_j_uː_ˌeɪ_t_ə]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.