INIENCEPHALY
\ɪnˈi͡ənsɪfəli], \ɪnˈiənsɪfəli], \ɪ_n_ˈiə_n_s_ɪ_f_ə_l_i]\
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Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
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