IGNAZ GJORGJIC

\ˈɪɡnaz d͡ʒˈiːd͡ʒˈɔːɡd͡ʒɪk], \ˈɪɡnaz d‍ʒˈiːd‍ʒˈɔːɡd‍ʒɪk], \ˈɪ_ɡ_n_a_z dʒ_ˈiː_dʒ_ˈɔː_ɡ_dʒ_ɪ_k]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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