HUNTERIAN CHANCRE
\hʌntˈi͡əɹɪən t͡ʃˈankə], \hʌntˈiəɹɪən tʃˈankə], \h_ʌ_n_t_ˈiə_ɹ_ɪ__ə_n tʃ_ˈa_n_k_ə]\
Definitions of HUNTERIAN CHANCRE
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A syphilitic chancre when attended with marked induration and ulceration; the only form of syphilitic chancre described by John Hunter.
By Smith Ely Jelliffe
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.