HIPPOCRATIC

\hˌɪpəkɹˈatɪk], \hˌɪpəkɹˈatɪk], \h_ˌɪ_p_ə_k_ɹ_ˈa_t_ɪ_k]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison
 
1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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