GROSSIERETE

\ɡɹˈə͡ʊsi͡əɹˌiːt], \ɡɹˈə‍ʊsi‍əɹˌiːt], \ɡ_ɹ_ˈəʊ_s_iə_ɹ_ˌiː_t]\

Definitions of GROSSIERETE

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1895 - Glossary of terms and phrases
By Henry Percy Smith

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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