GANGLIIFORM
\ɡˈaŋɡlɪˌɪfɔːm], \ɡˈaŋɡlɪˌɪfɔːm], \ɡ_ˈa_ŋ_ɡ_l_ɪ__ˌɪ_f_ɔː_m]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.