GAIT APRAXIA
\ɡˈe͡ɪt ɐpɹˈe͡ɪksi͡ə], \ɡˈeɪt ɐpɹˈeɪksiə], \ɡ_ˈeɪ_t ɐ_p_ɹ_ˈeɪ_k_s_iə]\
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Impaired ambulation not attributed to sensory impairment or motor weakness. FRONTAL LOBE disorders; BASAL GANGLIA DISEASES (e.g., PARKINSONIAN DISORDERS); DEMENTIA, MULTI-INFARCT; ALZHEIMER DISEASE; and other conditions may be associated with gait apraxia.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.