FISSURE OF GLASER

\fˈɪʃəɹ ɒv ɡlˈe͡ɪsə], \fˈɪʃəɹ ɒv ɡlˈe‍ɪsə], \f_ˈɪ_ʃ_ə_ɹ ɒ_v ɡ_l_ˈeɪ_s_ə]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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