ERF, EIF 2 RECYCLING FACTOR
\ˈiː ˌɑːɹˈɛf], \ˈiː ˌɑːɹˈɛf], \ˈiː_ ˌɑː_ɹ_ˈɛ_f]\
Sort: Oldest first
-
A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, eiF-2 kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of eIF-2, leading to the inhibition of protein synthesis. EC 2.7.10.-
By DataStellar Co., Ltd