ENT17,798

\ˈɛnt sˈɛvəntiːn θˈa͡ʊzənd sˈɛvənhˈʌndɹədən nˈa͡ɪntiˈe͡ɪt], \ˈɛnt sˈɛvəntiːn θˈa‍ʊzənd sˈɛvənhˈʌndɹədən nˈa‍ɪntiˈe‍ɪt], \ˈɛ_n_t s_ˈɛ_v_ə_n_t_iː_n θ_ˈaʊ_z_ə_n_d_ s_ˈɛ_v_ə_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n n_ˈaɪ_n_t_i__ˈeɪ_t]\

Definitions of ENT17,798

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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