DYE EXCLUSION ASSAYS, ANTITUMOR
\dˈa͡ɪ ɛksklˈuːʒən ɐsˈe͡ɪz], \dˈaɪ ɛksklˈuːʒən ɐsˈeɪz], \d_ˈaɪ ɛ_k_s_k_l_ˈuː_ʒ_ə_n ɐ_s_ˈeɪ_z]\
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Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumor growth parameters in laboratory animals.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.