DISSEMINATED NEURODERMATITIS
\dɪsˈɛmɪnˌe͡ɪtɪd njˌuːɹə͡ʊdəmɐtˈa͡ɪtɪs], \dɪsˈɛmɪnˌeɪtɪd njˌuːɹəʊdəmɐtˈaɪtɪs], \d_ɪ_s_ˈɛ_m_ɪ_n_ˌeɪ_t_ɪ_d n_j_ˌuː_ɹ_əʊ_d_ə_m_ɐ_t_ˈaɪ_t_ɪ_s]\
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A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.