COH.CC13

\kˈə͡ʊ dˈɒt sˌiːsˈiː θˈɜːtiːn], \kˈə‍ʊ dˈɒt sˌiːsˈiː θˈɜːtiːn], \k_ˈəʊ d_ˈɒ_t s_ˌiː_s_ˈiː θ_ˈɜː_t_iː_n]\

Definitions of COH.CC13

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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