CLOTH CAP
\klˈɒθ kˈap], \klˈɒθ kˈap], \k_l_ˈɒ_θ k_ˈa_p]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.