ASCLEPLAD

\ɐsklˈɛplad], \ɐsklˈɛplad], \ɐ_s_k_l_ˈɛ_p_l_a_d]\

Definitions of ASCLEPLAD

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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