APOLIPOPROTEINS E
\ˈapəlˌɪpəpɹˌə͡ʊtiːnz ˈiː], \ˈapəlˌɪpəpɹˌəʊtiːnz ˈiː], \ˈa_p_ə_l_ˌɪ_p_ə_p_ɹ_ˌəʊ_t_iː_n_z ˈiː]\
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Prominent protein constituents of plasma VLDL, chylomicrons, and a subfraction of HDL as well as of remnant lipoproteins which are derived from the lipoprotein lipase-mediated intravascular catabolism of triglyceride-rich lipoproteins. Apolipoproteins E are recognized by the LDL receptor and Apo E receptor. Any defect in the Apo E metabolism leads to increased plasma Apo E levels. A strong association has been found between high levels of Apo E and type III hyperlipoproteinemia.
By DataStellar Co., Ltd
